Diabetes Online-Kongress 2021
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Prof. Dr. Peter Kovacs
Prof. Dr. Peter KovacsDate of Birth: 08.07.1970Gender: MaleInstitute Address: Medizinische Klinik und Poliklinik III - Endokrinologie, Nephrologie, Rheumatologie, Universitätsklinikum Leipzig, Liebigstraße 21, 04103 Leipzig Phone: +49 341 / 97 15892 E-mail: peter.kovacs@medizin.uni-leipzig.deCurrent Position: Associate Professor for “Genetics of obesity and diabetes”Children: 1Academic Training: 1995–1998 PhD Student, Institute of Pathophysiology, University of Greifswald (Advisors: Prof. Klöting, Prof. Walther)1993–1995 PhD Student, Comenius University, Bratislava (Slovakia) (Advisor: Prof. P. Svec)1988–1993 Pharmaceutical Faculty, Comenius University Bratislava (Slovakia)Scientific Certificates:2008 Habilitation in Biochemistry (“Genetics of complex diseases – type 2 diabetes”; Prof. Stumvoll), Universität Leipzig1998 Dissertation (PhD in Pathophysiology) (“Animal model to dissect genetics of complex diseases“), University of Greifswald (Advisors: Prof. Klöting, Prof Walther)1993 Mgr – Master of Science (“Stress induced lipid peroxidation in the rat”; Advisor: Prof. Svec), Comenius University, BratislavaProfessional Career:2013–present IFB Professor for “Genetics of obesity and diabetes”, Leipzig University2007–2013 Head of the junior research group „Molecular mechanisms of the metabolic syndrome“ at the Interdisciplinary Centre for Clinical Research (IZKF), Leipzig University2004–2007 Junior Scientist, Department of Internal Medicine III, Leipzig University (Prof. Stumvoll)2000–2004 Research fellow and Postdoc, Phoenix Epidemiology and Clinical Research Branch, National Institutes of Health (NIH), Phoenix, AZ, USA (Dr. Bogardus) 1998–2000 Research fellow and Postdoc, Medical faculty, University of Greifswald (Prof. Klöting)Scientific Activities, Honors, Awards:2005 Menarini research award of the German Diabetes Society2002 Fellow Award for Research Excellence - National Institutes of Health, USA1996 Fellowship of the British Council - Editorial activities (associate and review editor) in scientific journals (Diabetes, Frontiers in Endocrinology, Experimental and Clinical Endocrinology and Diabetes); member of the PhD review board of the Medical Faculty of University of Leipzig; head of the Internal Review Board of the IFB AdiposityDiseases at the University of Leipzig; member of the Board of Directors at IFB, University of Leipzig.Most Important Publications:• Massier L*, Chakaroun R*, Tabei S, Crane A, Didt KD, Fallmann J, von Bergen M, Haange S-B, Heyne H, Stumvoll M, Gericke M, Dietrich A, Blüher M, Musat N, Kovacs P. (2020) Adipose Tissue Derived Bacteria are Associated with Inflammation in Obesity and Type 2 Diabetes. Gut 69:1796-1806.• Keller M, Yaskolka Meir A, Bernhart SH, Gepner Y, Shelef I, Schwarzfuchs D, Tsaban G, Zelicha H, Hopp L, Müller L, Rohde K, Böttcher Y, Stadler PF, Stumvoll M, Blüher M, Kovacs P*, Shai I*. (2020) DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial. Genome Med 12, 97 (https://doi.org/10.1186/s13073-020-00794-7).• Kovacs P. (2019) Setting our adipoSIGHTS on stem cells in pharmacogenomics. Cell Stem Cell 24 (2), 206-207• Derikx MH*, Kovacs P*, Scholz M*, Masson E, Chen J-M, Ruffert C, Lichtner P, te Morsche RHM, Cavestro GM, Algül H, Berg T, Bödeker H, Blüher M, Bruno MJ, Buch S, Bugert P, Cichoz-Lach H, Dabrowski A, Farré A, Frank J, Gasiorowska A, Geisz A, Goni E, Grothaus J, Grützmann R, Haas S, Hampe J, Hellerbrand C, Hegyi P, Huster D, Ioana M, Iordache S, Jurkowska G, Keim V, Krulisova V, Landt O, Di Leo M, Lerch MM, Lévy P, Löhr M, Macek M, Malats N, Malecka-Panas E, Mariani A, Martorana D, Mayerle J, Mora J, Mössner J, Müller S, Ockenga J, Pedrazzoli S, Pereira SP, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rohde K, Sack S, Saftoiu A, Schneider A, Schulz H-U, Soyka M, Simon P, Skipworth J, Stickel F, Stumvoll M, Testoni PA, Tönjes A, Treiber M, Weiss FU, Werner J, Wodarz N, Férec C, Drenth JPH, Witt H, Rosendahl J. Polymorphisms at PRSS1–PRSS2 and CLDN2–MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut. 2015; 64:1426-33.• Tönjes A*, Scholz M*, Breitfeld J, Marzi C, Grallert H, Gross A, Ladenvall C, Schleinitz D, Krause K, Kirsten H, Laurila E, Kriebel J, Thorand B, Rathmann W, Groop L, Prokopenko I, Isomaa B, Beutner F, Kratzsch J, Thiery J, Fasshauer M, Klöting N, Gieger C, Blüher M, Stumvoll M, Kovacs P. Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLoS Genet. 2014;10:e1004854.• Holstein A, Patzer O, Machalke K, Holstein JD, Stumvoll M, Kovacs P. Considerably increasing incidence of severe hypoglycemia 2007-2010 versus 1997-2000 – A German longitudinal population-based study. Diab Care. 2012;35:972-5.• Böttcher Y*, Unbehauen H*, Klöting N, Ruschke K, Körner A, Schleinitz D, Tönjes A, Enigk B, Dietrich K, Koriath M, Scholz GH, Tseng Y, Schön MR, Kiess W, Stumvoll M, Blüher M, Kovacs P. Adipose Tissue Expression and Genetic Variants of the Bone Morphogenetic Protein Receptor 1A Gene (BMPR1A) are Associated with Human Obesity. Diabetes. 2009;58:2119-28.• Kovacs P, Kress R, Rocha J, Kurtz U, Miquel JF, Méndez-Sánchez N, Bock HH, Schirin-Sokhan R, Stumvoll M, Mössner J, Lammert F, Wittenburg H. Variation of the Gene Encoding the Nuclear Bile Salt Receptor FXR and Gallstone Susceptibility in Mice and Humans. J Hepatol. 2008;48:116-24.• Kovacs P*, Geyer M*, Berndt J, Klöting N, Graham TE, Böttcher Y, Enigk B, Tönjes A, Schleinitz D, Schön MR, Kahn BB, Blüher M, Stumvoll M. Effects of Genetic Variation in the Human Retinol Binding Protein-4 Gene (RBP4) on Insulin Resistance and Fat Depot Specific mRNA Expression. Diabetes. 2007;56:3095-100.• Dina C, Meyre D, Gallina S, Durand E, Körner A, Jacobson P, Carlsson LMS, Kiess W, Vatin V, Lecoeur C, Delplanque J, Pattou F, Ruiz J, Weill J, Levy-Marchal C, Horber F, Potoczna N, Hercberg S, Le Stunff C, Kovacs P, Bougnères P, Marre M, Balkau B, Chèvre J-C, Froguel P. Variation in the fatso (FTO) gene contributes to both childhood obesity and severe adult obesity in the European population. Nat Genet. 2007;39:724-6.• Kovacs P, Harper I, Hanson RL, Infante AM, Bogardus C, Tataranni PA, Baier LJ. A Novel Missense Substitution (Val1483Ile) in the Fatty Acid Synthase Gene (FAS) is Associated with Percentage of Body Fat and Substrate Oxidation Rates in Non-Diabetic Pima Indians. Diabetes. 2004;53:1915-9.• Rjasanowski I, Klöting I, Kovacs P. Significantly disturbed sex ratio in offspring of mothers with insulin-dependent diabetes. Lancet. 1998;351:497-8.*Equally contributed.Scientific Collaborations • A. Fassano (Boston, USA) Alteration of intestinal permeability in metabolic diseases• E. Zeggini (Cambridge, UK) Rare genetic variants in the pathophysiology of metabolic syndrome• Y-H. Tseng (Boston, USA) Genetics of fat distribution• L. Baier, C. Bogardus (Phoenix, USA) Genetics of type 2 diabetes• D. Meyre (Hamilton, Canada) Genetics of obesity• H. Al-Hasani (Düsseldorf, Germany) The role of vaspin in obesity• P. Franks (Lund, Sweden) Gene - environment interaction
Uniklinik Leipzig Germany
  • Vortrag Bakterielle Translokation im Fettegewebe bei Diabetes Speaker
    Datum: 13.05.2021 , Zeit: 11:09 | Thema: Grundlagenwissenschaft
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  • Session Diabetes – Ein Defekt der Gene? Vorsitz
    Datum: 13.05.2021 , Zeit: 15:00 | Thema: Grundlagenwissenschaft
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