Ph.D. (Cell Biology, 2009), University of Padova, Italy
Since January 2021
Group leader, Metabolic Physiology, Institute for Diabetes and Cancer, Helmholtz Munich, Germany.
November 2013-December 2020
Postdoc, lab of Henriette Uhlenhaut, Molecular Endocrinology, Institute for Diabetes and Obesity, Helmholtz Munich, Germany.
May 2009-October 2013
Postdoc, lab of Stefano Schiaffino, Venetian Institute of Molecular Medicine (VIMM), Padova, Italy.
January 2006-April 2009
Ph.D. Student supervised by Stefano Schiaffino, Department of Biomedical Sciences, University of Padova, Italy.
May 2004-September 2005
Research assistant, lab of Fiona Inglis, Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana, USA.
RESEARCH FUNDING, AWARDS AND PRIZES
2022-2025 DFG/TRR333-1 “BATenergy”
2020-2021 DZD Grant 2020/21 “Circadian regulation of skeletal muscle insulin sensitivity by TBC1D1 Isoforms”
2019-2020 ExNet-0041-Phase2-3 (“SyNergy-HMGU”), Initiative and Network Fund of the Helmholtz Association
2018 EMBO Poster prize, “Nuclear Receptors and Biological Networks,” Crete, Greece
2013 Keystone Symposia Future of Science Fund Scholarship
2012 Travel award, "EMBO|EMBL Symposium: Diabetes and Obesity," Heidelberg, Germany
2003 Georges Lurcy Research Grant, Tulane University
SELECTED PUBLICATIONS 2017-2022
(*equal contribution, † corresponding author, [OA] open access)
1. Sato S*, Dyar KA*, Treebak JT*, Jepsen SL, Ehrlich AM, Ashcroft SP, Trost K, Kunzke T, Prade VM, Small L, Basse AL, Schönke M, Chen S, Samad M, Baldi P, Barrès R, Walch A, Moritz T, Holst JJ, Lutter D, Zierath JR, Sassone-Corsi P., Atlas of Exercise Metabolism Reveals Time-Dependent Signatures of Metabolic Homeostasis. Cell Metab. (2022). Feb 1;34(2):329-345.e8. [OA].
2. Artati A, Prehn C, Lutter D, Dyar KA†. Untargeted and Targeted Circadian Metabolomics Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) and Flow Injection-Electrospray Ionization-Tandem Mass Spectrometry (FIA-ESI-MS/MS). In: Solanas, G., Welz, P.S. (eds) Circadian Regulation. Methods Mol Biol. (2022). vol 2482. Humana, New York, NY.
3. Tokarz J, Möller G, Artati A, Huber S, Zeigerer A, Blaauw B, Adamski J, Dyar KA†. Common Muscle Metabolic Signatures Highlight Arginine and Lysine Metabolism as Potential Therapeutic Targets to Combat Unhealthy Aging. Int J Mol Sci. (2021). Jul 26;22(15):7958. [OA].
4. Dyar KA, Artati A, Cecil A, Adamski J. Skeletal Muscle Metabolomics for Metabolic Phenotyping and Biomarker Discovery. Omics Approaches to Understanding Muscle Biology. Meth. in Physiology. (2019).
5. Dyar KA*, Lutter D*, Artati A, Ceglia NJ, Liu Y, Armenta D, Jastroch M, Schneider S, de Mateo S, Cervantes M, Abbondante S, Tognini P, Orozco-Solis R, Kinouchi K, Wang C, Swerdloff R, Nadeef S, Masri S, Magistretti P, Orlando V, Borrelli E, Uhlenhaut NH, Baldi P, Adamski J, Tschöp MH, Eckel-Mahan K, Sassone-Corsi P. Atlas of Circadian Metabolism Reveals System-wide Coordination and Communication between Clocks. Cell. (2018) Sep 6;174(6):1571-1585.e11. [OA].
6. Dyar KA†, Hubert MJ, Mir AA, Ciciliot S, Lutter D, Greulich F, Quagliarini F, Kleinert M, Fischer K, Eichmann TO, Wright LE, Peña Paz MI, Casarin A, Pertegato V, Romanello V, Albiero M, Mazzucco S, Rizzuto R, Salviati L, Biolo G, Blaauw B, Schiaffino S, Uhlenhaut NH†. Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock. PLoS Biol. (2018). Aug 10;16(8):e2005886. [OA].
7. Dyar KA, Eckel-Mahan KL. Circadian Metabolomics in Time and Space. Front Neurosci. (2017). Jul 11;11:369. [OA].
Helmholtz Zentrum München
Germany
Vortrag
Muscle-specific clock and its influence on insulin resistance
Speaker