08:30 Uhr
Herausforderungen und Stärken der KI für seltene Erkankungen im Kindes- und Jugendalter Bone2Gene
B. Javanmardi (Bonn, DE)
09:50 Uhr
DGKJ-FV 26:
New way to determine total and direct Bilirubin non-invasively by SpectralPad
C. Haarer (Konstanz, DE)
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Autor:innen:
C. Haarer (Konstanz, DE)
J. Haarer (Konstanz, DE)
I. Albert (Wädenswil, CH)
D. Fehr (Winterthur, CH)
R. Hagen (Winterthur, CH)
L. Giesbrecht (Winterthur, CH)
M. Wüst (Winterthur, CH)
F. Spano (Winterthur, CH)
M. Bonmarin (Winterthur, CH)
Our innovative, small and energy-efficient wearable sensor can quickly and reliably measure Bilirubin non-invasively through the skin. Total Bilirubin but also direct Bilirubin can be determined. Current devices on the market lack sensitivity and are only able to determine total Bilirubin without differentiation between direct / conjugated (2 sugar molecules added in the liver) and indirect / unconjugated Bilirubin. For example, Philipps lists an accuracy of 1.5mg/dl total Bilirubin for its “BiliCheck” System. As 1.2mg/dl is regarded as upper limit for adults the use of current devices is limited to the niche of neonate jaundice.
To solve this issue, we developed a new and comparatively more precise patent-pending optical technology to determine total (and direct) Bilirubin non-invasively with a small wearable device emitting blue light and measuring the resulting fluorescence changes at different wavelengths.
We will present further results obtained in collaboration with the Zurich University of Applied Sciences (Sensors and Measuring Systems group) demonstrating good agreement between in-vivo and in-vitro experiments and validating the proof of concept of our technology.